参考文献
1.黄永棋，刘志荣．天然无序蛋白质：序列-结构-功能的新关系．物理化学学报，2010，26（8）：2061-2072.
2.王盼盼．食品中蛋白质的功能特性综述．肉类研究，2010，22（5）：62-71.
3.尹稳，伏旭，李平．蛋白质组学的应用研究进展．生物技术通报，2014，1（31）：32-38.
4.李莉．松仁多肽的制备及其免疫活性研究．哈尔滨：东北林业大学，2008.
5.林治华，全学军，周跃钢．多肽序列的结构特征与其免疫原性关系的研究．重庆工学院学报，2003（1）：12-17.
6.余勃．枯草芽孢杆菌发酵豆粕生产大豆活性多肽的研究．南京：南京农业大学，2006.
7.Gómara MJ，Sánchez-Merino V，Paús A，et al.Definition of an 18-mer Synthetic Peptide Derived from the GB virus C E1 Protein as a New HIV-1 Entry Inhibitor.Biochimica et Biophysica Acta（BBA）-General Subjects，2016，1860（6）：1139-1148.
8.Lacou L，Léonil J，Gagnaire V.Functional properties of peptides：From single peptide solutions to a mixture of peptides in food products.Food Hydrocolloids，2016，57 ：187-199.
9.Jiang Z，Wang L，Che H，et al. Effects of temperature and pH on angiotensin-I-converting enzyme inhibitory activity and physicochemical properties of bovine casein peptide in aqueous Maillard reaction system. LWT -Food Science and Technology，2014，59（1）：35-42.
10.Suwal S，Roblet C，Amiot J，et al. Presence of free amino acids in protein hydrolysate during electroseparation of peptides：Impact on system efficiency and membrane physicochemical properties. Separation and Purification Technology，2015，147 ：227-236.
11.Thansandote P，Harris RM，Dexter HL，et al. Improving the passive permeability of macrocyclic peptides：Balancing permeability with other physicochemical properties. Bioorganic & Medicinal Chemistry，2015，23（2）：322-327.
12.Zou Y，Wang W，Li Q，et al. Physicochemical，functional properties and antioxidant activities of porcine cerebral hydrolysate peptides produced by ultrasound processing. Process Biochemistry，2016，51（3）：431-443.
13.Yuan B，Ren J，Zhao M，et al. Effects of limited enzymatic hydrolysis with pepsin and highpressure homogenization on the functional properties of soybean protein isolate. LWT -Food Science and Technology，2012，46（2）：453-459.
14.Milbeo P，Maurent K，Moulat L，et al. N-Pyrrolidine-based α/β-peptides incorporating ABOC，a constrained bicyclic β-amino acid，for asymmetric aldol reaction catalysis. Tetrahedron，2016，72（13）：1706-1715.
15.张鹏军．碱性氨基酸在多肽质谱断裂中作用机理的研究．济南：山东大学，2012.
16.Li YQ. Structure Changes of Soybean Protein Isolates by Pulsed Electric Fields. Physics Procedia，2012，33 ：132-137.
17.黄文秀，郭庆启，石彦国，等．酪蛋白非磷酸肽对大豆多肽的修饰及复合物的乳化性表征．食品科学，2014，35（9）：157-161.
18.江晨，孙杰，毕洁，等．花生多肽的理化性质及抗氧化性质研究．花生学报，2013，42（3）：32-37.
19.于泓鹏，陈运生，吴克刚，等．罗非鱼酶解多肽的乳化性及乳化稳定性研究．中国食品添加剂，2015（2）：94-100.
20.朱艳华．玉米多肽的制备、理化性质及生物活性的研究．武汉：华中农业大学，2007.
21.Davis JP，Doucet D，Foegeding EA. Foaming and interfacial properties of hydrolyzed β-lactoglobulin. Journal of Colloid and Interface Science，2005，288（2）：412-422.
22.Diniz RS，Coimbra JSdR，Teixeira ÁVNdC，et al. Production，characterization and foamability of α-lactalbumin/glycomacropeptide supramolecular structures. Food Research International，2014，64 ：157-165.
23.Concu R，Dea-Ayuela MA，Perez-Montoto LG，et al. 3D entropy and moments prediction of enzyme classes and experimental-theoretic study of peptide fingerprints in Leishmania parasites. Biochimica et Biophysica Acta（BBA）-Proteins and Proteomics，2009，1794（12）：1784-1794.
24.Gordon NC，Lien S，Johnson J，et al. Multiple Novel Classes of APRIL-specific Receptorblocking Peptides Isolated by Phage Display. Journal of Molecular Biology，2010，396（1）：166-177.
25.Marrero-Ponce Y，Contreras-Torres E，García-Jacas CR，et al. Novel 3D bio-macromolecular bilinear descriptors for protein science：Predicting protein structural classes. Journal of Theoretical Biology，2015，374 ：125-137.
26.Milletti F. Cell-penetrating peptides：classes，origin，and current landscape. Drug Discovery Today，2012，17（15-16）：850-860.
27.van Hateren A，Bailey A，Werner JM，et al. Plasticity of empty major histocompatibility complex class I molecules determines peptide-selector function. Molecular Immunology，2015，68（2，Part A）：98-101.
28.Li Z，Dilger JM，Pejaver V，et al. Intrinsic size parameters for palmitoylated and carboxyamidomethylated peptides. International Journal of Mass Spectrometry，2014，368 ：6-14.
29.Liu S，Riesen A，Liu Z. Differentiating the role of different-sized microorganisms in peptide decomposition during incubations using size-fractioned coastal seawater. Journal of Experimental Marine Biology and Ecology，2015，472 ：97-106.
30.Bluhm MEC，Knappe D，Hoffmann R. Structure-activity relationship study using peptide arrays to optimize Api137 for an increased antimicrobial activity against Pseudomonas aeruginosa. European Journal of Medicinal Chemistry，2015，103 ：574-582.
31.Du H，Samuel RL，Massiah MA，et al. The structure and behavior of the NA-CATH antimicrobial peptide with liposomes. Biochimica et Biophysica Acta（BBA）-Biomembranes，2015，1848（10，Part A）：2394-2405.
32.Goux E，Lespinasse Q，Guieu V，et al. Fluorescence anisotropy-based structure-switching aptamer assay using a peptide nucleic acid（PNA）probe. Methods，2016，97 ：69-74.
33.Kristensen O. Crystal structure of the G3BP2 NTF2-like domain in complex with a canonical FGDF motif peptide. Biochemical and Biophysical Research Communications，2015，467（1）：53-57.
34.Lipp AM，Ji B，Hager R，et al. Micro-structured peptide surfaces for the detection of highaffinity peptide-receptor interactions in living cells. Biosensors and Bioelectronics，2015，74 ：757-763.
35.Petit VW，Rolland JL，Blond A，et al. A hemocyanin-derived antimicrobial peptide from the penaeid shrimp adopts an alpha-helical structure that specifically permeabilizes fungal membranes. Biochimica et Biophysica Acta（BBA）-General Subjects，2016，1860（3）：557-568.
36.Siow HL，Gan CY. Extraction，identification，and structure-activity relationship of antioxidative and α-amylase inhibitory peptides from cumin seeds（Cuminum cyminum）. Journal of Functional Foods，2016，22 ：1-12.
37.Tapadar S，Fathi S，Raji I，et al. A structure-activity relationship of non-peptide macrocyclic histone deacetylase inhibitors and their anti-proliferative and anti-inflammatory activities. Bioorganic & Medicinal Chemistry，2015，23（24）：7543-7564.
38.Wang C，He H，Zhang JL，et al. High performance liquid chromatography（HPLC）fingerprints and primary structure identification of corn peptides by HPLC-diode array detection and HPLC-electrospray ionization tandem mass spectrometry. Journal of Food and Drug Analysis，2016，24（1）：95-104.
39.刁小琴，张有林，关海宁．天然活性多肽及其应用前景．粮食与油脂，2006（5）：43-45.
40.代春华．黄粉虫幼虫蛋白酶解制备降血压肽的研究．无锡：江南大学，2012.
41.林琳．鱼皮胶原蛋白的制备及胶原蛋白多肽活性的研究．青岛：中国海洋大学，2006.
42.闵建华．蚕蛹蛋白活性多肽的酶法制备．西安：陕西师范大学，2009.
43.张墨楠．酶促水解大豆分离蛋白制备铁螯合肽的研究．杭州：中国计量学院，2013.
44.张研宇．超声波提取蚕蛹蛋白及酶法制备水溶性蚕蛹多肽的生物活性研究．西安：陕西师范大学，2011.
45.Li S，Yang X，Zhang Y，et al. Enzymolysis kinetics and structural characteristics of rice protein with energy-gathered ultrasound and ultrasound assisted alkali pretreatments. Ultrasonics Sonochemistry，2016，31：85-92.
46.Qu W，Ma H，Jia J，et al. Enzymolysis kinetics and activities of ACE inhibitory peptides from wheat germ protein prepared with SFP ultrasound-assisted processing. Ultrasonics Sonochemistry，2012，19（5）：1021-1026.
47.Zou Y，Ding Y，Feng W，et al. Enzymolysis kinetics，thermodynamics and model of porcine cerebral protein with single-frequency countercurrent and pulsed ultrasound-assisted processing. Ultrasonics Sonochemistry，2016，28 ：294-301.
48.Sanjukta S，Rai AK. Production of bioactive peptides during soybean fermentation and their potential health benefits. Trends in Food Science & Technology，2016，50 ：1-10.
49.Sedaghat F，Yousefzadi M，Toiserkani H，et al. Chitin from Penaeus merguiensis via microbial fermentation processing and antioxidant activity. International Journal of Biological Macromolecules，2016，82 ：279-283.
50.Wu R，Yu M，Liu X，et al. Changes in flavour and microbial diversity during natural fermentation of suan-cai，a traditional food made in Northeast China. International Journal of Food Microbiology，2015，211：23-31.
51.房耀维，余勃，王淑军，等．发酵法制备沙光鱼多肽及其抗氧化活性．食品科学，2010，31（17）：298-301.
52.马丽杰．发酵法制备鳕鱼皮胶原多肽及脱腥机理研究．烟台：烟台大学，2013.
53.庞伟．猪血多肽的发酵法制备及其ACE抑制活性研究．合肥：合肥工业大学，2009.
54.张树华．发酵法制备绿豆多肽．济南：齐鲁工业大学，2014.
55.de la Fuente-Núñez C，Cardoso MH，de Souza Cândido E，et al. Synthetic antibiofilm peptides. Biochimica et Biophysica Acta（BBA）-Biomembranes，2016，1858（5）：1061-1069.
56.Gauna A，Losada S，Lorenzo M，et al. Synthetic peptides for the immunodiagnosis of hepatitis A virus infection. Journal of Immunological Methods，2015，427 ：1-5.
57.Liu X，Marrakchi M，Xu D，et al. Biosensors based on modularly designed synthetic peptides for recognition，detection and live/dead differentiation of pathogenic bacteria. Biosensors and Bioelectronics，2016，80 ：9-16.
58.Quandt A，Espona L，Balasko A，et al. Using synthetic peptides to benchmark peptide identification software and search parameters for MS/MS data analysis. EuPA Open Proteomics，2014，5 ：21-31.
59.Trier NH，Holm BE，Slot O，et al. Application of synthetic peptides for detection of anticitrullinated peptide antibodies. Peptides，2016，76 ：87-95.
60.Verbeke F，Wynendaele E，Braet S，et al. Quality evaluation of synthetic quorum sensing peptides used in R&D. Journal of Pharmaceutical Analysis，2015，5（3）：169-181.
61.Borg J，Georgitsi M，Aleporou-Marinou V，et al. Genetic recombination as a major cause of mutagenesis in the human globin gene clusters. Clinical Biochemistry，2009，42（18）：1839-1850.
62.L’Hélias C，Proust J. Genetic recombination and DNA transpositions induced by pteridines and extracts of pteridine-treated diapausing chrysalids and mutants injected in Drosophila melanogaster. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis，1995，328（1）：91-111.
63.冯云，杨华蓉，黄宁，等．高迁移率蛋白-17（HMG-17）基因重组多肽的制备及其抗菌结构域的研究．生物医学工程学杂志，2005，22（4）：773-777.
64.Lafarga T，Aluko RE，Rai DK，et al. Identification of bioactive peptides from a papain hydrolysate of bovine serum albumin and assessment of an antihypertensive effect in spontaneously hypertensive rats. Food Research International，2016，81 ：91-99.
65.Nongonierma AB，FitzGerald RJ. The scientific evidence for the role of milk protein-derived bioactive peptides in humans：A Review. Journal of Functional Foods，2015，17 ：640-656.
66.Wang QM，Gao Z，Liu S，et al. Hybrid polymeric micelles based on bioactive polypeptides as pH-responsive delivery systems against melanoma. Biomaterials，2014，35（25）：7008-7021.
67.Zeng WC，Zhang WC，Zhang WH，et al. Antioxidant activity and characterization of bioactive polypeptides from bovine hair. Reactive and Functional Polymers，2013，73（3）：573-578.
68.Daughaday WH. Endocrinology-The way we were：A personal history of somatomedin. Growth Hormone & IGF Research，2006，16 ：3-5.
69.Enberg G. Purification of a high molecular weight somatomedin binding protein from human plasma. Biochemical and Biophysical Research Communications，1986，135（1）：178-182.
70.Fröhlander N，von Schoultz B. Growth hormone and somatomedin C during post-menopausal replacement therapy with oestrogen alone and in combination with an antioestrogen. Maturitas，1988，9（4）：297-302.
71.Furman BL. Somatomedins. xPharm：The Comprehensive Pharmacology Reference. New York：Elsevier，2008 ：1-16672.
72.Salbe AD，Hill CH，Veillon C，et al. Relationship between serum somatomedin C levels and tissue selenium content among adults living in a seleniferous area. Nutrition Research，1993，13（4）：399-405.
73.Barkley-Levenson AM，Ryabinin AE，Crabbe JC. Neuropeptide Y response to alcohol is altered in nucleus accumbens of mice selectively bred for drinking to intoxication. Behavioural Brain Research，2016，302 ：160-170.
74.Barrell GK，Ridgway MJ，Wellby M，et al. Expression of regulatory neuropeptides in the hypothalamus of red deer（Cervus elaphus）reveals anomalous relationships in the seasonal control of appetite and reproduction. General and Comparative Endocrinology，2016，229 ：1-7.
75.Barson JR，Leibowitz SF. Hypothalamic neuropeptide signaling in alcohol addiction. Progress in Neuro-Psychopharmacology and Biological Psychiatry，2016，65 ：321-329.
76.Hammock EAD. Neuropeptides in Mental Health：CRF，AVP，and OXT A2 -Friedman，Howard S. Encyclopedia of Mental Health（Second Edition）. Oxford：Academic Press，2016 ：193-196.
77.Inaba A，Komori Y，Muroi Y，et al. Neuropeptide Y signaling in the dorsal raphe nucleus inhibits male sexual behavior in mice. Neuroscience，2016，320 ：140-148.
78.Qin ZL，Yang LQ，Li N，et al. Clinical study of cerebrospinal fluid neuropeptides in patients with primary trigeminal neuralgia. Clinical Neurology and Neurosurgery，2016，143 ：111-115.
79.Reichmann F，Holzer P. Neuropeptide Y：A stressful review. Neuropeptides，2016，55 ：99-109.
80.Saraf R，Mahmood F，Amir R，et al. Neuropeptide Y is an angiogenic factor in cardiovascular regeneration. European Journal of Pharmacology，2016，776 ：64-70.
81.Cardot Martin E，Michel A，Raynal B，et al. Community-acquired meticillin-resistant Staphylococcus aureus strain USA300 resists staphylococcal protein A modulation by antibiotics and antimicrobial peptides. International Journal of Antimicrobial Agents，2015，45（1）：19-24.
82.Dosler S，Mataraci E. In vitro pharmacokinetics of antimicrobial cationic peptides alone and in combination with antibiotics against methicillin resistant Staphylococcus aureus biofilms. Peptides，2013，49 ：53-58.
83.Samy RP，Thwin MM，Stiles BG，et al. Novel phospholipase A2 inhibitors from python serum are potent peptide antibiotics. Biochimie，2015，111 ：30-44.
84.Schulze M，Dathe M，Waberski D，et al. Liquid storage of boar semen：Current and future perspectives on the use of cationic antimicrobial peptides to replace antibiotics in semen extenders. Theriogenology，2016，85（1）：39-46.
85.Nimalaratne C，Bandara N，Wu J. Purification and characterization of antioxidant peptides from enzymatically hydrolyzed chicken egg white. Food Chemistry，2015，188 ：467-472.
86.Orsini Delgado MC，Nardo A，Pavlovic M，et al. Identification and characterization of antioxidant peptides obtained by gastrointestinal digestion of amaranth proteins. Food Chemistry，2016，（197，Part B）：1160-1167.
87.Sila A，Bougatef A. Antioxidant peptides from marine by-products：Isolation，identification and application in food systems. A review. Journal of Functional Foods，2016，21 ：10-26.
88.Vásquez-Villanueva R，Marina ML，García MC. Identification by hydrophilic interaction and reversed-phase liquid chromatography–tandem mass spectrometry of peptides with antioxidant capacity in food residues. Journal of Chromatography A，2016，1428 ：185-192.
89.Wattanasiritham L，Theerakulkait C，Wickramasekara S，et al. Isolation and identification of antioxidant peptides from enzymatically hydrolyzed rice bran protein. Food Chemistry，2016，192 ：156-162.
90.Cabrales-Rico A，de la Torre BG，Garay HE，et al. Bio-analytical method based on MALDIMS analysis for the quantification of CIGB-300 anti-tumor peptide in human plasma. Journal of Pharmaceutical and Biomedical Analysis，2015，105 ：107-114.
91.Fujinami N，Yoshikawa T，Sawada Y，et al. Enhancement of antitumor effect by peptide vaccine therapy in combination with anti-CD4 antibody：Study in a murine model. Biochemistry and Biophysics Reports，2016，5 ：482-491.
92.Gu R，He Y，Han S，et al. Pharmacokinetics and bioavailability of tuftsin-derived T peptide，a promising antitumor agent，in beagles. Drug Metabolism and Pharmacokinetics，2016，31（1）：51-56.
93.He H，Sun L，Ye J，et al. Enzyme-triggered，cell penetrating peptide-mediated delivery of antitumor agents. Journal of Controlled Release，2016，240 ：67-76.
94.Su T，Yang H，Fan Q，et al. Enhancing the circulating half-life and the antitumor effects of a tumor-selective cytotoxic peptide by exploiting endogenous serum albumin as a drug carrier. International Journal of Pharmaceutics，2016，499（1-2）：195-204.
95.Agyei D，Ongkudon CM，Wei CY，et al.Bioprocess challenges to the isolation and purification of bioactive peptides. Food and Bioproducts Processing，2016，98 ：244-256.
96.Aluko RE. 5-Amino acids，peptides，and proteins as antioxidants for food preservation A2-Shahidi，Fereidoon. Handbook of Antioxidants for Food Preservation.UK：Woodhead Publishing，2015 ：105-140.
97.de Castro RJS，Sato HH. Biologically active peptides：Processes for their generation，purification and identification and applications as natural additives in the food and pharmaceutical industries. Food Research International，2015，74 ：185-198.
98.Kadam SU，Tiwari BK，Álvarez C，et al. Ultrasound applications for the extraction，identification and delivery of food proteins and bioactive peptides. Trends in Food Science &Technology，2015，46（1）：60-67.
99.Chirita RI，Chaimbault P，Archambault JC，et al. Development of a LC-MS/MS method to monitor palmitoyl peptides content in anti-wrinkle cosmetics. Analytica Chimica Acta，2009，641（1-2）：95-100.
100.Goebel C，Aeby P，Ade N，et al. Guiding principles for the implementation of non-animal safety assessment approaches for cosmetics：Skin sensitisation. Regulatory Toxicology and Pharmacology，2012，63（1）：40-52.
101.Ghodake G，Kim DY，Jo JH，et al. One-step green synthesis of gold nanoparticles using casein hydrolytic peptides and their anti-cancer assessment using the DU145 cell line. Journal of Industrial and Engineering Chemistry，2016，33 ：185-189.
102.Iavicoli P，Urbán P，Bella A，et al. Application of Asymmetric Flow Field-Flow Fractionation hyphenations for liposome–antimicrobial peptide interaction. Journal of Chromatography A，2015，1422 ：260-269.
103.Khara JS，Lim FK，Wang Y，et al. Designing α-helical peptides with enhanced synergism and selectivity against Mycobacterium smegmatis：Discerning the role of hydrophobicity and helicity. Acta Biomaterialia，2015，28 ：99-108.
104.Lakshmaiah Narayana J，Chen JY. Antimicrobial peptides：Possible anti-infective agents. Peptides，2015，72 ：88-94.
105.Maria-Neto S，de Almeida KC，Macedo MLR，et al. Understanding bacterial resistance to antimicrobial peptides：From the surface to deep inside. Biochimica et Biophysica Acta（BBA）-Biomembranes，2015，1848（11）：3078-3088.
106.Meloni BP，Milani D，Edwards AB，et al. Neuroprotective peptides fused to arginine-rich cell penetrating peptides：Neuroprotective mechanism likely mediated by peptide endocytic properties. Pharmacology & Therapeutics，2015，153 ：36-54.
107.Sedaghati M，Ezzatpanah H，Mashhadi Akbar Boojar M，et al. Isolation and identification of some antibacterial peptides in the plasmin-digest of β-casein. LWT-Food Science and Technology，2016，68 ：217-225.
108.Lafarga T，Hayes M. Bioactive peptides from meat muscle and by-products：generation，functionality and application as functional ingredients. Meat Science，2014，98（2）：227-239.
109.Sarika，Iquebal MA，Rai A. Biotic stress resistance in agriculture through antimicrobial peptides. Peptides，2012，36（2）：322-330.
110.Zhou C，Hu J，Ma H，et al. Antioxidant peptides from corn gluten meal：Orthogonal design evaluation. Food Chemistry，2015，187 ：270-278.